Mixed Lymphocyte Reactions

Of all the cell-based assays that we perform here at Xeno Diagnostics, the category that we receive the most questions about is undoubtedly Mixed Lymphocyte Reactions (MLR’s). Though the concept is fairly simple, the actual process of designing, performing, and interpreting MLR’s can be a daunting task. Throughout this resource, we will discuss the following:

If you are in need of a service provider for an MLR, or need additional information, please see the following resources:

  • Xeno Diagnostics' process for working with clients / request a quote or teleconference
  • Xeno Diagnostics' experience and capabilities with MLR (Cell types, species, applications)
  • MLR run under GLP compliance vs RUO / discovery
  • Setup and Optimization of Mixed Lymphocyte Reactions
  • Mixed Lymphocyte Reaction FAQ's
  • Mixed Lymphocyte Tumor Cell Culture (MLTuC) for Cancer Drug Screening
  • Other T-Lymphocyte & Innate Immune Cell Activation Assays